Leftover Turkey Skillet Pot Pie with Flaky Biscuits: The Coziest Thanksgiving Comeback

Last Updated on October 24, 2025 by Chef Josie

There’s something deeply satisfying about turning Thanksgiving leftovers into a meal that feels brand new. This Leftover Turkey Skillet Pot Pie takes tender turkey, creamy vegetables, and golden, buttery biscuits and brings them together into the ultimate comfort food. It’s the kind of dish that makes you forget you’re eating leftovers; rich, creamy, and full of flavor that feels like home.

When the fridge is full of bits and pieces after the big feast, this recipe is your secret weapon. It’s quick to throw together, uses one pan, and fills the kitchen with that warm, irresistible aroma of buttery biscuits and herbs. I love making this the day after Thanksgiving when all you want is something cozy, hearty, and effortless.

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Why You’ll Love This Leftover Turkey Skillet Pot Pie

• One-Pan Wonder: Fewer dishes, more flavor.
• Perfect for Leftovers: A delicious way to use up turkey and veggies.
• Flaky and Comforting: The golden biscuits soak up the creamy sauce perfectly.
• Quick and Easy: Ready in under 40 minutes.
• Family Favorite: Everyone loves a warm, bubbling pot pie.

Ingredient Breakdown

• Leftover Turkey: Shredded or diced, about 2 cups.
• Mixed Vegetables: Use a combination of peas, carrots, and corn (fresh, frozen, or leftover).
• Butter and Flour: To make a rich, thick roux base for the sauce.
• Chicken or Turkey Broth: Adds flavor and moisture to the filling.
• Milk or Cream: For that luscious, creamy texture.
• Onion and Garlic: Bring depth and aroma.
• Herbs: Fresh rosemary or thyme add a cozy, savory note.
• Biscuits or Puff Pastry: The flaky topping that makes this pot pie irresistible.

Substitutions:

• Use rotisserie chicken instead of turkey if needed.
• Swap biscuits for puff pastry or pie crust.
• Add chopped mushrooms or green beans for more veggies.

Step-by-Step Instructions

1. Preheat Oven: Set to 400°F (200°C).
2. Make the Filling: In an oven-safe skillet, melt butter and sauté onions until soft. Stir in garlic, then add flour to form a roux.
3. Add Liquids: Slowly whisk in broth and milk until smooth and thickened.
4. Add Turkey and Veggies: Stir in the turkey, vegetables, herbs, salt, and pepper. Let simmer for 5 minutes.
5. Top with Biscuits: Place biscuit dough on top of the filling.
6. Bake: Transfer skillet to oven and bake for 20–25 minutes, until biscuits are golden and filling is bubbly.
7. Serve: Sprinkle with extra herbs and enjoy hot from the skillet.

Notes and Top Tips

• Use cold biscuit dough for a flakier top.
• Don’t overfill the skillet; the sauce will bubble as it bakes.
• Add a touch of cream cheese to the filling for extra richness.
• For a crisp bottom layer, bake the biscuits halfway before adding to the skillet.

Serving Suggestions and Variations

• Serve with a simple green salad or cranberry sauce for balance.
• Add diced sweet potatoes or mushrooms for a hearty twist.
• For a festive touch, sprinkle grated Parmesan or a little nutmeg on top before baking.

Storage and Reheating Tips

• Store: Keep leftovers in an airtight container for up to 3 days.
• Reheat: Warm in a 350°F oven until bubbly and hot, or microwave individual portions.
• Freeze: Freeze the unbaked filling and top with fresh biscuits when ready to cook.

Conclusion

This Leftover Turkey Skillet Pot Pie with Flaky Biscuits takes your Thanksgiving leftovers to a whole new level. Creamy, savory, and wrapped in golden layers of buttery dough, it’s everything you love about comfort food in one skillet.

Make this the day after your holiday feast and give your leftovers a second life worth celebrating. If you try it, leave a comment and let me know how your family liked it; I bet it becomes your new favorite post-holiday tradition.

FAQs

1. Can I use puff pastry instead of biscuits?
Yes! Puff pastry gives it a more traditional pot pie crust. Just lay it over the top, crimp the edges, and bake until golden.

2. What if I don’t have an oven-safe skillet?
Make the filling in a regular pan, then transfer it to a baking dish before topping and baking.

3. Can I make this ahead of time?
Yes, assemble the filling and refrigerate for up to 24 hours. Add the biscuit topping right before baking.

4. How can I make it dairy-free?
Use olive oil instead of butter and substitute unsweetened almond milk or oat milk for dairy milk.

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